[1] He is a three-time Olympian (1996, 2000, and 2004), a two-time swimmer at the Asian Games (2002 and 2006), and a former Uzbekistani age group record holder in the 100 and 200 m freestyle.

Agafonov made his official debut at the 1996 Summer Olympics in Atlanta, where he competed as a member of the Uzbekistan team in the 4 × 200 m freestyle relay.

Teaming with Vyacheslav Kabanov, Dmitry Pankov, and Oleg Tsvetkovskiy, Agafonov swam the second leg in heat two with a split of 1:56.44, but the Uzbeks settled for fourth place and twelfth overall in a final time of 7:40.60.

[2] At the 2000 Summer Olympics in Sydney, Agafonov competed as an individual swimmer in the 100 m freestyle.

Swimming in heat three, he picked up a third seed and fifty-fourth overall by 0.36 of a second behind winner Paul Kutscher of Uruguay in 52.58.