Her music has been performed by the Kronos Quartet, Glimmerglass Opera with Cincinnati Opera, Serbian National Theater, English National Ballet, Rambert Dance, Sybarite5, Jorge Caballero, the Sausalito Quartet, ETHEL, Dušan Týnek Dance Theatre, Ijsbreker, Moravian Philharmonic, Belgrade Philharmonic, and Festival Ballet Providence, among others.
Vrebalov’s cross-disciplinary interests led to participation at residencies and fellowships that include the MacDowell Colony, Djerassi, The Hermitage, New York’s New Dramatists, Rockefeller Bellagio Center, American Opera Projects, and the Other Minds Festival.
Between 2007 and 2011, Vrebalov created and led Summer in Sombor (Serbia), a weeklong composition workshop with the South Oxford Six composers’ collective that she co-founded in 2002 in New York City.
Vrebalov is a full time professor of composition at the Academy of Arts in Novi Sad; she previously taught at the City College of New York.
Vrebalov's orchestral works include commissions for the Seattle Youth Symphony Orchestra, This Kiss for the Whole World, inspired by Beethoven's Ninth Symphony and premiered in 2022; Our Voices (2019), for "surround orchestra" deployed throughout the audience and including a virtual reality component by artist Derek Ham; the multipart Sea Ranch Songs, (2019) inspired by California's Sea Ranch; her accordion concerto Forgotten Anthems IV (2018), composed for Goran Stevanovic, Orbits (2002), and Times (1996), which received the Vienna Modern Masters Award.
2 in 1997, Vrebalov has maintained an especially fruitful relationship with the Kronos Quartet,[4] resulting in 20 works to date including three commissioned for the group by New York's Carnegie Hall: ...hold me, neighbor, in this storm..., My Desert, My Rose, and iletrikés rímes.
Following research in rural China in 2016, Vrebalov composed two works for traditional Chinese instruments, Cosmic Love III and Light Codes, for the Forbidden City Chamber Orchestra and conductor Liu Shun.