The oldest known member of the lineage was the Frankish count Willehmus, a Burgundian who is thought to have gone to the Carolingian Kingdom of Italy around 888 or 889, possibly to aid Guy III of Spoleto in his quest for the Iron Crown of Lombardy.
His son Aleramo, received from King Hugh of Italy the first feudal domains in Central Liguria in the year 933, later confirmed by Holy Roman Emperor Otto the Great, who in addition granted him and his descendants the hereditary title of Marchio or Margrave of the Holy Roman Empire.
Despite their constant territorial division between the multiple male descendants, the Aleramici managed to maintain control over an important part of the Piedmont and the Eastern flank of the Ligurian Bay, forming powerful alliances throughout the ruling houses of Europe, including the Capetians and the Hohenstaufens.
The cadet line of Monferrato gained notable influence and power through their involvement in the Crusades, becoming kings and queens of Jerusalem, first by marriage and then by succession in the 12th century.
Despite the extinction of their cadet branch, the Aleramici survived the Middle Ages through the multiple descending branches of the Marquises of Savona, including the Marquises of Saluzzo (from 1135 to 1548), Finale (ruled by the Aleramici del Carreto from 1135 to 1602), Ceva, Busca, Clavesana, Loreto, Bosco, Belforte, Ussecio, Pareto, Varazze, Ponzone, amongst others, whose domains were mostly absorbed by the Republic of Genoa between the 12th and 14th centuries.