[1][2] A native of Milan, Alessio di Siregno was ordained a priest in the Order of Friars Minor.
He refused to accept the appointment, and made an appeal to the ecumenical council which was being contemplated, and which actually took place in Constance beginning in November 1414.
[6] The mere mention of an appeal to a council brought him a letter from Pope John dated 12 January 1412, ordering the officials of the bishops of Nice, Embrun, and Grenoble, to expel Bishop Alessio from Gap and incarcerate him.
[8] In 1425, with the consent of Pope Martin V, he granted possession of the monastery of San Sisto to the Benedictine Order of Monte Cassino of S. Giustino of Padua.
[9] He attended the Council of Basel, which was summoned by Martin V, and which opened on 14 December 1431[10] He served as Bishop of Piacenza until his death in Cremona on 1 January 1447.