Alex Anisi (died 18 February 2012) was a Papua New Guinean politician.
He was Premier of East Sepik Province from June 1993 to August 1995, and subsequently served as secretary-general of the People's Progress Party for two parliamentary terms until 2011.
He was a candidate for the National Parliament at the 2012 election when he died suddenly during the campaign.
His son, Ezekiel Anisi, subsequently entered politics himself.
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