The couple married on 16 May 1840 in Kensington Old Church, despite the initial objections of his mother over Lucie's lack of a dowry.
Following the birth of their son, Maurice, in 1849, Lady Duff-Gordon began to succumb to tuberculosis, and by the winter of 1861, she had become so ill that her doctors advised her to travel to a warmer, drier climate.
She reached Alexandria in October 1862 and, except for two short visits to England in 1863 and 1865, she remained there for her health and separated from her husband until her death in 1869.
He became a senior clerk in the Treasury in 1854, and a Commissioner of Inland Revenue in 1856; he was also Assistant Gentleman Usher of the Privy Chamber to Her Majesty.
It records "his beloved wife Lucie, only daughter of John and Sarah Austin, who died and was buried in Egypt."
There is also an inscription regarding Sir Alexander and Lucie's youngest child, Urania, who was born in November 1858 and died on 22 September 1877.