He was secretary and treasurer of the Trustees of Cincinnati College, responsible for pulling the institution out of debt after poor financial practices and two significant fires.
[7] Winthrop B. Smith planned to publish a series of elementary English text books, known as the McGuffey Readers.
[5] In 1845, McGuffey became secretary and treasurer of the Trustees of Cincinnati College when the institution was in debt and had suffered fires that gutted the school building.
He was then the President of the Board of Trustees of the Miami Medical College and Director of McMicken University.
[9] His tastes led him to seek the quieter walks of business, and the greater part of his life was spent in chamber practice as a counselor, especially in the management of trusts and the settlement of estates.
In arguments he was logical and keen rather than oratorical, and took pleasure in the analysis of strictly legal questions rather than in appeals to a jury.