In 2001, he became the governor of Taymyr Autonomous Okrug in northern Siberia, holding that position until 2002.

[3] Khloponin won the election for governor of Krasnoyarsk Krai against Alexander Uss, another man with major business links.

[5][6] President Vladimir Putin on May 12 replaced Khloponin as envoy with the Interior Ministry Lt. Gen. Sergey Melikov[7]

In 2002, Alexander Khloponin was named Person of the Year by Expert magazine, a Russian business weekly.

Khloponin's daughter, Lyubov Khloponina, studied at the London School of Economics.