His parents were Grigori Grigorovich Kushelev (1754-1833) and his wife Ljubov' Il'inična Bezborodko (1783-1809).
[citation needed] He was strongly influenced by his aunt, princess Lobanov-Rostov.
After graduating he left St Petersburg for Tartu (where he met Georg Friedrich Parrot) and Berlin (where he inspected the University).
He was elected an honorary member of the Russian Academy of Sciences in 1830 and seven years later was made director of the Treasury Department.
[citation needed] On 30 January 1829 he married Aleksandra Nikolaevna Repnina-Volkonskaja (1805-1836), daughter of Nikolai Repnin-Volkonsky and Varvara Alekseevna Razumovskaja.