A Republican, Speirs represented Cumberland County in the Maine Senate from 1923 to his death in 1927.
While in office, Speirs promoted education and opposed raising the gas tax.
Having grown up in Portland, Speirs settled in Westbrook, Maine, where he spent the final 31 years of his life.
Speirs died suddenly on October 9, 1927, at St. Barnabas Hospital in Woodfords and was interred at Woodlawn Cemetery in Westbrook.
His funeral was attended by many important political figures, including current Governor Owen Brewster, former Governor Percival Baxter, current President of the Maine Senate Frank H. Holley as well as Senators Arthur Spear, Raymond Oakes and Paul Slocum.