[1][2] In 2011, she took part in season 8 of reality musical talent show Operación Triunfo, ranking fourth in the final standings.

[4][5] Masangkay's film debut came with her performance as Teresa in historical drama 1898, Our Last Men in the Philippines (2016).

[3] As a musical theatre actress she has played Nala in The Lion King at Teatro Lope de Vega and Kiki in Flashdance.

[1][6] In 2019, she featured in dystopian film The Platform, portraying Miharu, a sadistic prisoner desperately searching for her offspring.

[3] In 2022, she played Wendy, a Philippine migrant domestic worker in La Moraleja, in spy thriller Code Name: Emperor.