Alexandria is a village in Thayer County, Nebraska, United States.

[5] The first permanent white residents of the county arrived in 1858, settling about two and a half miles (about four kilometers) south of present-day Alexandria, on the divide between the Little Blue and Big Sandy Creek.

In 1859, Isaac Alexander arrived from Kansas with a portable gristmill; he settled on Big Sandy Creek, where he built a log cabin and stockade.

At the railroad's behest, the Nebraska Land and Town Company platted towns along its route, naming them in alphabetical order; the easternmost of these was Alexandria, followed by Belvidere, Carleton, and Davenport.

[5] The town was named after Isaac Alexander's son, S. J. Alexander, who had been involved in negotiating the railroad's route through Thayer County, and who later served as Nebraska's Secretary of State.

[7] The town supported a flour mill on Big Sandy Creek; a newspaper, the Alexandrian, was established in 1879; and by 1882, there were four churches.

[7][8] According to the United States Census Bureau, the village has a total area of 0.40 square miles (1.04 km2), all land.

40.2% of all households were made up of individuals, and 20.8% had someone living alone who was 65 years of age or older.

40.4% of all households were made up of individuals, and 26.3% had someone living alone who was 65 years of age or older.