Deshler is a city in Thayer County, Nebraska, United States.

[3] Deshler was established in 1887 when the Chicago, Rock Island and Pacific Railroad was extended to that point.

[5][6] It was named for John G. Deshler, the original owner of the town site.

[7][8][5] According to the United States Census Bureau, the city has a total area of 0.51 square miles (1.32 km2), all land.

The racial makeup of the city was 99.3% White, 0.4% Native American, and 0.3% from two or more races.

36.0% of all households were made up of individuals, and 18.7% had someone living alone who was 65 years of age or older.