[1][2][3][4] Born in Sainte-Foy-lès-Lyon, Rhône, Carrel was raised in a devout Catholic family and was educated by Jesuits, though he had become an agnostic by the time he became a university student.
Working as an intern at a Lyon hospital, he developed a technique for suturing small blood vessels using extremely fine needles.
[1] In 1902, Carrel underwent a transformative experience that led him from being a skeptic of the reported visions and miracles at Lourdes to a believer in spiritual cures.
While there he collaborated with American physician Charles Claude Guthrie in work on vascular suture and the transplantation of blood vessels and organs as well as the head.
[10] In the 1930s, Carrel and Charles Lindbergh became close friends not only because of the years they worked together but also because they shared personal, political, and social views.
[10] Due to his close proximity with Jacques Doriot's fascist Parti Populaire Français (PPF) during the 1930s and his role in implementing eugenics policies during Vichy France, he was accused after the Liberation of collaboration, but died before the trial.
This method, which involved wound debridement and irrigation with a high volume of antiseptic fluid, was a significant medical advancement in the absence of antibiotics.
[17] This innovation is considered to be a significant advancement in the fields of open-heart surgery and organ transplantation, and it paved the way for the development of the artificial heart, which became a reality many years later.
[22] In 1912, Carrel began an experiment at the Rockefeller Institute for Medical Research, where he cultured tissue from an embryonic chicken heart in a stoppered Pyrex flask of his own design.
[26] Despite the doubts surrounding Carrel's experiment, it remains an important part of scientific history, and his work on tissue culture had a significant impact on the development of modern medicine.
In February 2002, to celebrate the 100th anniversary of Charles Lindbergh's birth, the Lindbergh-Carrel Prize was established by the Medical University of South Carolina at Charleston.
In the 1936 German introduction of his book, Carrel added praise for the Nazi regime at the publisher's request, which did not appear in other language editions.
[37] After the second world war the book and his role with the Vichy regime would stain his reputation such that his name was removed from streets in more than 20 French cities and the Alexis Carrel Medical Faculty in Lyon was renamed in 1996.
However, in 1941, Carrel went on to advocate for the creation of the French Foundation for the Study of Human Problems (Fondation Française pour l'Etude des Problèmes Humains).
Carrel's connections to the cabinet of Vichy France president Philippe Pétain, specifically French industrial physicians André Gros and Jacques Ménétrier, helped pave the way for the creation of the foundation.
[4] The foundation played a significant role in the establishment of the field of occupational medicine, which was institutionalized by the Provisional Government of the French Republic (GPRF) through the 11 October 1946 law.
The foundation's efforts were not limited to occupational medicine and extended to other areas such as demographics, economics, nutrition, habitation, and opinion polls.
This certificate aimed to ensure the good health of spouses, particularly regarding sexually transmitted diseases (STDs) and "life hygiene."
The Foundation underwent a purge and emerged shortly afterward as the Institut national d'études démographiques (INED), which is still active today.