Afterwards he embarked on an autobiographical cycle that included the feature-length Family Portrait Sittings (1975)[2] and Scenes from Childhood (1979),[3] both premiered at the Whitney Museum of American Art.
In the late 1980s he began a series of conversations with anthropologist Ákos Östör that resulted in Seed and Earth (1994),[6] a portrayal of life in a Bengali village, and Khalfan and Zanzibar (1999),[7] which poses the question of an individual's relation to his culture.
Around 1993 Guzzetti became interested in the experimental possibilities of the new small video formats and began a series of videos that included What Actually Happened (1996), Under the Rain (1997), A Tropical Story (1998), The Tower of Industrial Life (2000), which was shown in the 2002 Whitney Biennial, Down from the Mountains (2002),[8] Calcutta Intersection (2003), History of the Sea (2004), and most recently, Still Point (2009) and Passage (2018).
This experimental strain is related to his collaborations with composers, including his contributions to Earl Kim’s Exercises en Route (1971), as well as to Kurt Stallmann’s SONA (2005).
He also worked collaboratively with Kurt Stallmann on Breaking Earth (2008), a gallery installation for 11 channels of sound and 5 video projections; Moon Crossings (2011), for 15 instruments, electronics and video; the single-channel Time Present (2013); Among Rivers (2019) for 7 projectors, 28 loudspeakers, and four performers; and Open Air (2023) with Kurt Stallmann and wind player Eric Mandat.