Alfredo Duhalde Vásquez (June 30, 1898 – April 10, 1985) was a Chilean politician who served twice as provisional president in 1946.

Later he dedicated himself to work his lands in the areas of Río Bueno and La Unión.

In 1945 he was elected a Senator for Valdivia, Osorno, Llanquihue, Aysén, Chiloé and Magallanes.

On August 3 of the same year, he stepped down once again in order to run in his party's primaries for the upcoming presidential election, which he lost to Gabriel González Videla, who went on to win the general election later that year.

He resumed as vice president on August 13, having been replaced in the interim by Vice Admiral Vicente Merino, and continued in office until October 17, when he finally stepped down completely, being replaced by his minister of the Interior, Juan Antonio Iribarren.