Crumpler attended New Hanover High School in Wilmington, North Carolina and was a letterman in football and track and field.

In football, he started as a tight end and as a linebacker, and as a senior, he was an All-Midwest 4-A Conference selection.

After graduating from high school, Crumpler attended the University of North Carolina at Chapel Hill.

His senior season concluded with him amassing 23 catches for 287 yards and one touchdown and he finished second in All-American voting.

Crumpler finished the regular season with 48 receptions for 774 yards and six touchdowns and was elected to the Pro Bowl.

In 2005, Crumpler returned to start 16 games for the Falcons, setting career highs with 65 receptions for 877 yards, as well as five touchdowns.

In December 2007, Crumpler was fined by the NFL for wearing black eye strips during a Monday Night Football which had the letters MV and the number 7 written on them in support of Vick, who was in prison at the time.

[6] However, Crumpler played in all 16 games for the Titans in 2009, starting 14 and catching 27 passes for 222 yards and one touchdown.

He was also part of a blocking unit that aided Titans running back Chris Johnson in a 2,006-yard rushing season.

Whether it's in a game, in practice, in a meeting, in a walk through, whether it's a decision on the play, whether it's the way his demeanor is at that particular time, he knows when to smile, he knows when to be serious, he knows when to [step up], when to back off, when to gear it up, when to say and do the right thing.

He is the son of East Carolina University Athletics Hall of Fame inductee (1980) and North Carolina Sports Hall of Fame inductee (2002) Carlester Crumpler Sr. and younger brother of former Seattle Seahawks and Minnesota Vikings tight end Carlester Crumpler.