He was selected by the Atlanta Falcons in the fourth round (99th overall) of the 2001 NFL draft, and in 2005, joined the Chicago Bears, spending ten seasons with the team.

Despite being an offensive lineman, a position not typically glorified in football, Garza was a fan favorite among Hispanic Americans across the United States.

In that season, the Bears reached a 39–14 victory over the New Orleans Saints, which allowed them to claim the NFC Championship and advance to Super Bowl XLI.

[11] Garza was also featured in a Modelo Beer commercial alongside fellow former Hispanic football players Tony Gonzalez and Anthony Muñoz.

Garza is a supporter and member of the United Way, a group of charitable organizations dedicated to helping less fortunate children and the elderly.

He has previously worked with the Empty Stocking Fund, the Atlanta Falcons' Feed The Homeless Campaign, and the Hall County Boys & Girls Club.