The line hosts passenger services connecting Algiers station with either Annaba or Constantine, the two largest cities in eastern Algeria.

Commuter rail services using this portion of the Algiers-Skikda line connect Algiers to Houari Boumediene Airport and Thénia, among others.

The Thénia–Constantine is not electrified and is single track from Thénia to Bordj Bou Arréridj and from Ramdane Djamel to Skikda.

[1] The portion between Sétif and the town of El Guerrah (in the municipality of Ouled Rahmoun) is being upgraded by SNTF.

Regional services connect Algiers to Sétif, Béjaïa (via the Béni Mansour-Bejaïa line), and M'Sila, Algeria.