Ali Mamlouk (Arabic: علي مملوك; born 19 February 1946) is a Syrian intelligence officer and special security and military advisor to President Bashar al-Assad.

[18][19] Samaha with the help of the former Lebanese Security Chief Jamil Al Sayyed "tried to carry out assassination" of Samir Geagea, Saad Hariri and Wissam al-Hassan.

[20] In May 2015, concern mounted regarding Mamlouk's whereabouts and health after not having been seen for some time, leading to comparisons with Rustum Ghazaleh who recently met a violent and unclear death.

Mamlouk and his Egyptian counterparts reportedly discussed the fight against Islamic State, and against other Islamist factions, including the Muslim Brotherhood.

[23] In 2018, Maj. Gen. Mamlouk made a rare visit to Cairo to meet with his Egyptian counterpart, Abbas Kamel, director of the GIS with discussing “political, security and counterterrorism issues”.

[30] In November 2018, French prosecutors issued international arrest warrants for three senior Syrian intelligence and government officials: Ali Mamlouk, Abdel Salam Mahmoud and Jamil Hassan.

[31] Four days of hearings at the Paris Cour d'assises started on 21 May 2024,[32] and on May 25 all three men were convicted in absentia of involvement in the torture and killing of two French citizens in Syria.