At some time between 1320 and 1323, Isabella of Armenia, Princess of Tyre, sister of King Oshin, along with her son Henri, were imprisoned and murdered by Alice's father.
Oshin wanted to reduce the number of claimants to the throne of the Cilician Kingdom.
[citation needed] Alice is known to have born Leo one child, a son called Hethum who died around 1331.
[citation needed] The treatment Leo meted out to his regent upon reaching his majority in 1329 was violent.
After he had Alice murdered, Leo took the opportunity to remarry to a western princess, Constance of Sicily; however, they had no children.