[2] Doctors determined that Weigel was born with complete androgen insensitivity syndrome, possessing XY chromosomes, a clitoris, and internal testes, and without a uterus or ovaries.
[5] Since 2017, Weigel has often advocated for legislative change at the Texas State Capitol in Austin, starting with her role as a director for Deeds Not Words—a non-profit organization focused on gender equality.
[1] The organization's founder, Democratic politician Wendy Davis, was her personal mentor and recruited Weigel to work for Deeds Not Words in 2016.
[1] Weigel was the campaign manager for Danielle Skidmore's City Council race, the first openly transgender person to run for public office in Texas.
[1] After consulting Davis and Skidmore, Weigel decided to come out as intersex before the Texas State Legislature while speaking against the proposed legislation.
[13][14] In 2023, Weigel partnered with Texas Health Action to launch the nation's first ever intersex care offering for adult patients through their Kind Clinics.