His art was widely acclaimed in his native Venezuela and abroad, winning him multiple awards and recognitions as one of the top Venezuelan plastic artists of the 20th century.

His infancy is spent in El Callao and his love for the plastic arts starts in elementary school where he drew his first drawings.

[1][3] In 1947 Rodriguez moves to Caracas and enrolls in the "Escuela de Artes Plasticas," where he has Marcos Castillo, Rafael Ramón González, Rafael Monasterios, César Prieto, Luis Alfredo López Méndez and Francisco Narváez, among others, as teachers.

In 1958, and until 1961, Alirio Rodriguez receives a scholarship of the Venezuelan Ministry of Education to travel to Italy where he studies at the Instituto D'Arte di Roma.

[3] Rodríguez’s work represented Venezuela at the XXXVII Venice International Art Biennial.