After graduating with a Baccalauréat diploma in humanities at Notre-Dame-de-Bury High School, (Margency), she took comedy classes at Cours Florent and Studio Pygmalion.
[1] After having participated in several television series and co-hosted the show Kawai on Filles TV alongside Louise Bourgoin, Wheeler won a role in the Saphia Azzeddine's adaption of Azzeddizine's novel Mon père est femme de ménage.
After a few small roles in popular comedies - Fonzy, by Isabelle Doval and À toute épreuve by Antoine Blossier - Wheeler acted in the dramedy Memories, by Jean-Paul Rouve, released in 2014.
However, Wheeler's new focus on cinema did not signal a total depart from news media, and in October 2015 she founded the column (Journal intime fictif) in the Antoine de Caunes's weekly show L'émission d'Antoine, broadcast on Canal+.
The same year, the actress won the role Mademoiselle Jeanne in Gaston Lagaffe [fr], an adaptation of the eponymous cartoon by Pierre-François Martin-Laval.