The graphic novel is a spin-off of the long-running series Hellblazer, published by the DC Comics imprint Vertigo.

[1] The graphic novel follows John Constantine's investigation into a worldwide phenomenon that is placing innocent people into comas.

[2] In 2004, mysterious plague begins putting its victims into unexplained comas, including Chas Chandler's granddaughter Tricia.

Constantine summons Beroul's enemies in a church and Mictlantecuhtli, immune to the effects of Christian holy paraphernalia, effortlessly slaughters them.

Stephen Holland of Comics Bulletin wrote in his review of the graphic novel that "Carey is on the toppest form I've known of him" and felt that the style evoked earlier periods of the long-running series as the "script felt like Ennis, the art like a moodier, more solid John Ridgway.