When the taxation roll of Pope Nicholas IV was drawn up in 1291, the rectory of Glossop was valued at £34 13s.

The nave was completely rebuilt in 1831, with removal and replacement of much of the old fabric including the tracery of the aisle windows.

The work was carried out by the firm of E. W. Drury of Sheffield, the cost far exceeding the initial estimate of £700 (equivalent to £80,287 in 2023).

When the nave was rebuilt in 1914 it was discovered that the arch leading to the chancel had been partly made up of plaster, the wall supported by this arch had not been bonded into the existing chancel walls, and the "oak" roof bosses were also plaster.

[3] It was the gift of churchwarden Harriet Jackson in memory of her husband Isaac, a local industrialist and great benefactor to the town.

This was replaced in 1984 by an organ from the Unitarian Church in Glossop which was originally from 1910 by Norman and Beard.

There was originally a separate bell-house in the churchyard which was a low building surrounded by railings but in 1709 the medieval bells were replaced by six bells described as "very deep in tone" which were bought from Woodford in Cheshire and installed in the tower.