From 2022 to 2024, Mills also portrayed antagonistic Heather Webber on the ABC soap opera, General Hospital, for which she received a Daytime Emmy Award for Outstanding Guest Performer in a Drama Series.

[3] Her stepmother was actress Genevieve (Ginette Marguerite Auger), and her stepfather was Chester B. Kerr, a director of Yale University Press.

[4] Mills began her career appearing in episodes of television series Mr. Novak and The Leslie Uggams Show, before making her big screen debut playing minor role in the 1970 comedy-drama film, Diary of a Mad Housewife.

[5] During the 1970s, Mills performed in a number of stage productions, such as Off-Broadway's A Colliers Friday Night, The Little Foxes, Voices, The Idol Makers and Says I, Says He.

During the 1990s, Mills acted in a number of made-for-television movies, such as Jonathan: The Boy Nobody Wanted (1992), Tainted Blood (1993) opposite Raquel Welch,[6] Moment of Truth: Caught in the Crossfire (1994),[7] Family Reunion: A Relative Nightmare (1995), and Deadline for Murder: From the Files of Edna Buchanan (1995) starring Elizabeth Montgomery in her last screen appearance.

[8] She also appeared in Roseanne, Touched by an Angel, NYPD Blue, Popular, Girlfriends, Sabrina the Teenage Witch, Strong Medicine and Yes, Dear.

[11] In October, 2022, Mills replaced Robin Mattson as legacy character Heather Webber on the ABC soap opera, General Hospital.