Natalie Miller's picture-perfect life is upended: she's diagnosed with breast cancer, her cheating boyfriend leaves her, and her job as an aide to a senator is on the line.

Jillian Westfield's living a “perfect” suburban life, with a successful husband and a sweet little toddler, but can’t help thinking “what if” about the choices she made seven years ago.

She took care of her younger sisters, her dad got sober, and fifteen years later she is married to her high-school sweetheart and trying for a baby.

Then a fortune-teller gives her the gift of clarity, and she can suddenly see terrible things happening before they occur, including her father's relapse and her husband's departure.

Willa has grown up under her father's belief system that everything happens for a reason and is beyond our control, which he wrote a bestselling book about.

Their love story is told in two arcs - one moving forward in time from Tatum's point of view, and one winding backwards from Ben's.