Alpha Iota Omicron (ΑΙΟ) is a South Asian interest and multicultural collegiate fraternity located in the United States.

Alpha Iota Omicron was a founding member of the APIA Greek Alliance, the former name of the National APIDA Panhellenic Association Alpha Iota Omicron was founded on October 16, 1998, at the University of Michigan as a South Asian interest fraternity by eighteen students.

[2][4] Its founding fathers were:[5] The fraternity was built on the core principles or pillars of Brotherhood, Networking, Community Service, and Cultural Competence.

[3] Over the years, Alpha Iota Omicron has expanded nationally, chartering ten chapters across the United States and Canada.

[2] Alpha Iota Omicron was a founding member of the APIA Greek Alliance, the former name of the National APIDA Panhellenic Association.