A sequel, Alpha Mission II, was released for the Neo Geo arcade system in 1991.

Alpha Mission is a one-player scrolling shooter game in its segregation of air-to-air and air-to-ground weapons.

Throughout each of the levels, the player must fight off waves of enemies that threaten several space stations and a boss must be defeated at the end of each.

[5][6] The game is also included on SNK 40th Anniversary Collection, containing both the original arcade and the NES version.

In Japan, Game Machine listed ASO on their December 1, 1985 issue as being the second most-successful table arcade cabinet of the month.