In 1973, after having achieved much success in rally, Alpine decided to turn its attention and commitment to endurance racing, where despite having participated since 1963, it had not yet obtained significant results.

An evolution of the A440 was prepared for the following season, equipped with a higher wheelbase, the Hewland FGA400 gearbox, and a lighter engine using magnesium and light alloys.

In their hands, Alpine-Renault won seven out of seven races and took the 1974 Marche continental title, while Alain Serpaggi's results earned him the European Drivers' Championship, in a 1-2-3 sweep ahead of his teammates Larrousse and Jabouille.

The following season the car was entrusted to private teams, while one example was equipped with a turbocharged engine by the American Garrett Systems to carry on the development of its heir, the A442.

An Alpine A441 was also part of the race in the Elf-Switzerland team; it is piloted by Marie-Claude Beaumont and Léa Lombardi who finished sixth.