Altarum traces its history back to 1946 as Willow Run Laboratory in Ypsilanti, Michigan.
In 2001, ERIM acquired Vector Research, Inc., a health care information system company, and changed its name to Altarum.
[2] In 2011, Altarum acquired Palladian Partners, a Maryland-based science, medical, and public health communications firm that serves government agencies and private companies.
[3] Altarum expanded its work into advanced data analytics and value-based payment in 2017 by integrating the Health Care Incentives Improvement Institute into its operations.
In 2018, Altarum released a report funded by the Kellogg Foundation on the economic benefits of eliminating racial disparities.