[9][10][11] In 2003–2004, the company expanded its offerings, debuting new ongoing titles by such cartoonists as Graham Annable, Scott Campbell, Damon Hurd, Nick Bertozzi, and Josh Neufeld, as well as a number of one-shots and graphic novels.

In July 2012, it was announced that Alternative Comics was resuming operations under the new general manager Marc Arsenault, owner of the publisher/distributor Wow Cool, and moving to Cupertino, California.

[12][13] (Wow Cool had been formed in 1990 by Arsenault, Tom Hart, and Sam Henderson,[14] so the company already had established relationships with a number of Alternative Comics' core cartoonists.)

"[19] Cartoonists who have published with Alternative include Graham Annable, Gabrielle Bell, Nick Bertozzi, Brandon Graham, Asaf Hanuka, Tomer Hanuka, Tom Hart, Dean Haspiel, Sam Henderson, James Kochalka, David Lasky, Jon Lewis, Matt Madden, Josh Neufeld, Dash Shaw, Jen Sorensen, and Sara Varon.

The company was also known as a distributor for Xeric Foundation award-winners, such as Leela Corman, Derek Kirk Kim, Neufeld, Bishakh Som, Sorensen, Karl Stevens, Lauren Weinstein, and many others.