Alternative ribosome-rescue factor B

Alternative ribosome-rescue factor B (ArfB, YaeJ) also known as peptidyl-tRNA hydrolase,[1] is a protein that plays a role in rescuing of stalled ribosomes.

[1] It works like a GGQ-release factor itself, releasing the peptide from tRNA.

[3] This gene is also found in eukaryotic organelles as MRPL58 (ICT1).

The similarity is high enough to be interchangeable.

[4] Its role has expanded to that of a codon-independent release factor, although it likely still functions in ribosomal rescue.