Altrincham and Sale was a parliamentary constituency in Greater Manchester, represented in the House of Commons of the Parliament of the United Kingdom.

The House of Commons (Redistribution of Seats) Act 1944 set up Boundary Commissions to carry out periodic reviews of the distribution of parliamentary constituencies.

It also authorised an initial review to subdivide abnormally large constituencies (those exceeding an electorate of 100,000) in time for the 1945 election.

The ensuing by-election (held in 1965) was won by Anthony Barber, who served as Edward Heath's Chancellor of the Exchequer.

Barber also entered the House of Lords, and at the October 1974 general election was succeeded by Fergus Montgomery, later Sir Fergus Montgomery, who served as Parliamentary Private Secretary to Margaret Thatcher, during her tenure as Secretary of State for Education, and then as Leader of the Opposition.