Realizing that their brother is cursed with lycanthropy, Alvin and Simon search for a way to cure Theodore, and save the play, without Dave finding out.

Finding no solutions, they decide to take up advice from psychic Madame Raya, who claims that Theodore will start behaving like an adult werewolf by the next full moon.

During the conversation, Talbot mentions an ancestor killed by silver bullets, one of which was made into the cane's wolf head, and turns into a werewolf under the light of the full moon.

Dave, realizing that Alvin was telling the truth about Talbot all along, hurries to the school to warn the students but is knocked unconscious after running into a pole.

At the wrap party, Mr. Talbot, expressing gratitude for his release from his family curse, announces he will succeed Milliken as the new school principal while she takes on a less stressful job.

[2] On September 4, 2007, the film was included in a two-disc DVD set with Alvin and the Chipmunks Meet Frankenstein titled "A Scare-riffic Double Feature", and re-released with a different cover on March 11, 2008.