Thomas is the University of Maryland's all-time leader in scoring, rebounding and double-doubles for both the women's and men's programs, and one of nine athletes in NCAAW history with six career triple-doubles.

[1] In her freshman season, Thomas was named 2011 ACC Rookie of the Year and was selected to the All-ACC Second Team.

[1] In her junior year, Thomas became the first person in NCAA or WNBA history to average over 18 points, 10 rebounds and 5 assists for an entire season.

[5] She won ACC Player of the Year for a second time and led the injury-addled Terrapins to the Sweet Sixteen in the NCAA Tournament.

[1] Thomas capped her collegiate career by earning 2014 ACC Player of the Year for a third straight season, in addition to AP, WBCA and USBWA First-Team All America honors.

She led a young Terrapins squad on a deep run through the NCAA Tournament, scoring a career-high 33 points against the Tennessee Lady Vols in the Sweet Sixteen en route to reaching the 2014 Final Four in Nashville.

In her first career playoff game, Thomas scored 20 points and grabbed 10 rebounds in an 88–83 loss to the Phoenix Mercury.

[11] On August 9, 2018, Thomas scored a season-high 22 points in a 101–92 victory over the Dallas Wings to help the Sun clinch a playoff spot.

[17] On November 12, 2024, it was announced that Thomas would appear and play in the inaugural 2025 season of Unrivaled, the women's 3x3 basketball league founded by Napheesa Collier and Breanna Stewart.

"[citation needed] During Game 2 of the 2021 semifinals against the Las Vegas Aces, Thomas dislocated her right shoulder.

[24] In February 2021, she and Connecticut Sun teammate, DeWanna Bonner, shared that they were in a relationship, and in July 2023 they became engaged.