[1] After graduating from Harry Ainlay Composite High School in Edmonton, Alberta, Plouffe committed to play at Utah.

She averaged 13.7 points and 7.3 rebounds per game, earning the Mountain West Freshman of the Year award and was named second-team all-conference.

Plouffe started all 32 games, averaging 14.1 points and 8.2 rebounds, notably recording a double-double against Washington in the 2012 WNIT.

She was named to the all-WNIT team, setting a WNIT record with 83 rebounds in the tournament, where they lost in the championship to Drexel.

Plouffe also competed at the 2015 FIBA Americas Women's Championship in her hometown of Edmonton, appearing in five of the team's six games.

at the 2017 AmeriCup in Buenos Aires, Plouffe averaged 5.3 points and 6.3 rebounds per game, the latter of which was her senior team career-high.

[14] Plouffe played in Canada's first 3x3 World Cup appearance at the 2022 edition in Antwerp alongside her twin sister Katherine.

After wins over the United States and Lithuania, Canada lost to France in the finals to take home silver.

[16][17] At the 2023 FIBA 3x3 World Cup in Vienna, Canada won their group before being upset in the quarterfinals by France, their second consecutive loss to the country, to place sixth.