Her 2000s work includes Mad magazine, and such DC Comics characters as Harley Quinn, Power Girl, and Atlee.

[1] She names as influences Joe Kubert, for teaching his students to compose pages as if they were to be devoid of any dialogue or word balloons, and Frank Miller for his pacing and his ability to create tension and intense action and reactions.

[3] After about her sixth or seventh time showing her portfolio, Marvel editor Greg Wright gave Conner her first illustration assignment, an 11-page Yellowjacket back-up story in Solo Avengers #12 (November 1988).

From 1993 to 1994 she penciled issues #1–10 of Peter David and Richard Howell's creator-owned series, Soulsearchers and Company, which was published by Claypool Comics.

Her commercial art work includes illustrations for the New York City advertising agencies Kornhauser & Calene, and Kidvertisers, for such accounts as Arm & Hammer, Playskool, and Nickelodeon.

[7] Nike, Inc. commissioned Conner and fellow comics artist Jan Duursema to design the Make Yourself: A Super Power advertising campaign in 2011.

[8] Conner did modeling/art reference work for the Marvel miniseries Elektra: Assassin in the 1980s, and for artist Joe Jusko's Punisher / Painkiller Jane in 2000.

They collaborated on the Terra miniseries, which premiered in November 2008,[9] and the first 12 issues of the Power Girl ongoing series,[10] which were published between 2009 and 2010, both of which Conner penciled.

[21] Conner's art was featured in "The Perspiration Implementation", the October 19, 2015, episode of the American sitcom The Big Bang Theory.

In the episode, comic book store owner Stuart Bloom asks the women for ideas on how to attract more women to his shop, and Amy Farrah Fowler (Mayim Bialik) points out that an illustration hanging on one of the shop's walls, "Girl on a Leash", may not be conducive to attracting female customers.

The image, which was illustrated by Conner and colored by Paul Mounts, depicts a scantily-clad woman being held on a chain leash by a muscular, whip-wielding masked man.

She also finds the Strathmore 300 series "pretty good", in that she appreciates its texture and greater affordability, but says that she must occasionally contend with getting a "bleedy batch".

[3] To ink her own artwork, she uses Staedtler .03, .01 and .005 technical pen, and will sometimes use a Copic .005 for extremely fine work, as these implements feel better in her hands than crowquills and brushes.

[2] As her artwork is open and lacks much shading, Conner feels that Paul Mounts is a compatible colorist for her work, as he achieves "the right amount of bounciness or moodiness, depending on what's needed."