Amaurosis (Greek meaning darkening, dark, or obscure) is vision loss or weakness that occurs without an apparent lesion affecting the eye.
Milton, already totally blind for twelve years (some scholars think from retinal detachment; others have diagnosed glaucoma) by the time he published Paradise Lost, refers to these terms in Book 3, lines 25–26.
Some patients only have retinal blindness, whereas others have multi-systemic involvement that includes renal, cardiac, skeletal, and, most notably, central nervous system anomalies.
[3] Theodor von Leber, a German ophthalmologist, described LCA in 1869 as a disorder characterized by profound visual loss present at or shortly after birth, nystagmus, sluggish pupillary reactions, and pigmentary retinopathy.
[3] Amaurosis fugax, also known as transient monocular blindness, is caused by a sudden, temporary decrease in blood flow to one eye.