Murray was also active in other businesses, including serving on the board of directors for several railroads and financial institutions.

As a director of the Erie Railroad, he used his connections to obtain free tickets and passes for runaway slaves, facilitating their escape to Canada.

During the American Civil War, Murray was a member of the committee that raised and equipped the 124th New York Volunteer Infantry Regiment.

[1] He remained at the store from 1824 to 1831, when he moved to Goshen, New York, to become a clerk at the Orange County Bank.

[5] His tenure was noted for his opposition to slavery; when Congress considered approval of the pro-slavery Lecompton Constitution for Kansas in 1858, Murray was in mourning for the death of one of his sons and attending to his ill wife, but left Goshen to return to Washington in time vote no.

[12] In the years before slavery was ended, Murray used his connection to the Erie Railroad to provide fugitive slaves free passes and tickets to aid them in escaping to Canada.

[13] During the American Civil War, Governor Edwin D. Morgan appointed committees of leading citizens in each of New York's counties to facilitate the recruiting and equipping of troops for the Union Army.

[14] Two of Murray's sons, George and Wisner, served in the Union Army as members of the 7th New York Volunteer Infantry Regiment.