It is endemic to Amazonian Peru and found in the lowlands adjacent to the northern end of the Eastern Andes.

It is threatened by habitat loss caused by agriculture (e.g., coffee and livestock production) and subsistence wood collection.

[1] The primary threat to the Cainarachi Poison Frog is the substantial loss of its natural forest habitat, driven by agricultural activities such as coffee, palm oil, and rice cultivation, as well as livestock production and subsistence wood collection.

As human activities continue to cause the loss of forested areas, the species faces a heightened risk of decline.

Research indicates that this ongoing habitat destruction could lead to a strong negative impact on the population dynamics of the frog.