[citation needed] Fox News reporter Shannon Bream often anchored the program during Kelly's absences.

Rick Folbaum and Juliet Huddy co-anchored the program occasionally, and Martha MacCallum has also served as a fill-in anchor for the show.

On July 3, 2013, Megyn Kelly announced on air that she would be taking maternity leave and no longer hosting America Live.

She also revealed that upon her return in the fall, she would be moving to a prime-time show, The Kelly File, beginning Monday, October 7, 2013.

From July 4, 2013, to September 27, 2013, the show was hosted by a rotation of Shannon Bream, Martha MacCallum, Alisyn Camerota, Gregg Jarrett and Heather Childers.