[1] The plane departed Little Rock National Airport with three crew and twenty-one passengers on board.

At 11:36 pm, approximately 29 kilometres (18 mi) southwest of Memphis Municipal Airport, the DC-3 descended at an angle of 20 degrees, the right wing slightly low, and struck the Mississippi River.

The Civil Aeronautics Board investigated the crash, but was unable to determine the probable cause of the accident.

The Board is unable to determine the probable cause of this accident upon the available evidence which has been collected in the present investigation.

Search for further information will continue and in the event that additional significant evidence is obtained a supplemental report will be issued.As of June 2023[update], Flight 2 is used on the Los Angeles-New York City (JFK) route, contrary to the convention of retiring flight numbers that have crashed.