Eastern Air Lines Flight 45 was a domestic commercial airline flight that had a mid-air collision with a USAAF A-26 Invader bomber over northeastern South Carolina on July 12, 1945, forcing an emergency landing in a field by the airliner, and resulting in the crash of the bomber.

According to "The State" newspaper on July 13, 1945 (page 1) the public relations office of the Florence Army Air Field last night issued the following statement: An Eastern Air Lines DC-3, bound for Miami from Washington miraculously escaped destruction at 2:45 this afternoon when its senior pilot, G. D. Davis, of Miami, Fla., brought his crippled ship in for a safe landing after a mid-air collision with a twin-motored military craft.

There were three fatalities, two of them military personnel, but except for the masterful handling of his plane by Pilot Davis, it is almost certain that the 17 passengers and three crew members of the airliner would also have perished.

In the collision the left engine of the airliner was torn off and the fuselage was badly cut just aft of the pilot's cockpit.

Despite this damage to his plane, Davis maintained full flight control and brought his ship in for an emergency landing.