The American Journal of Therapeutics is a bimonthly medical journal covering advances in drug therapy, comparative effectiveness research, and post-marketing surveillance.

The journal was established in 1994 by John Somberg MD and is published by Wolters Kluwer.

The editor-in-chief since 2015 is Peter Manu MD, Professor of Medicine at the Zucker School of Medicine at Hofstra/Northwell, Hofstra University, Hempstead, NY.

[1][failed verification] The journal has been part of the Web of Science Core Collection since 2010.

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