He began actively working in television as a producer-director in the eighties and set up Plus Channel in 1990 which was India’s first entertainment conglomerate and the largest independent producer of TV programmes.

Amit Khanna is the only permanent member of the Council of Management of the Producers Guild of India (the two others were V. Shantaram and Raj Kapoor).

Presently retired from all film activities and organisational responsibilities, Amit Khanna devotes all his time solely to writing.

In 1989 Khanna helped set up Plus Channel,[31] a television programming house, and joined it as managing director and Group Editor.

Under his tenure, the organization expanded its role to produce movies and music, and provide event management services.

[32][33][34] In May 2008 the company signed deals to produce and develop movies with prominent Hollywood actors such as Tom Hanks, Brad Pitt, George Clooney, Jim Carrey and Nicolas Cage.

As a lyricist he has penned over 200 Hindi film songs, working mainly with music directors like Bappi Lahiri, Rajesh Roshan and Laxmikant–Pyarelal.