It is endemic to Yunnan, China[1][3][4] and known from Wuliang and Ailao Mountains in Jingdong County.

[1][4] Once suspected to be synonym of Amolops mantzorum, its validity was confirmed with molecular methods in 2014.

The iris is brown with irregular bright small yellow spots.

[2] Amolops tuberodepressus inhabits montane rapids and streams with small waterfalls in evergreen broad-leaved forests at elevations of 1,500–2,400 m (4,900–7,900 ft) above sea level.

It is threatened by habitat loss caused by small-scale wood extraction and small hydroelectric dams.