Nekemias arborea, commonly known as pepper vine, is native to the Southeastern United States, Texas, and New Mexico.

It spreads rapidly, climbing up trees and bushes.

[1] It prefers moist soils such as stream banks, and disturbed areas.

[2] Its synonyms include: Ampelopsis arborea (L.) Koehne, Ampelopsis bipinnata Michx., Ampelopsis pinnata DC., Cissus arborea (L.) Des Moul., Cissus bipinnata Elliott, Cissus orientalis Lam., Cissus stans Pers., Hedera arborea (L.) Walter, Nekemias bipinnata Raf., Vitis arborea L., Vitis bipinnata Torr.

Nekemias arborea is used as an ornamental plant in gardens.