[2] A. alba has a diverse diet ranging from plant material to small vertebrates[2] (such as lizards and their eggs, snakes, mice, and other rodents).

[6] It occurs in South America from eastern Venezuela and the island of Trinidad through the entire Amazon Basin to northern Argentina.

[2] A. alba lays the greatest number of eggs at a time (8–16) in comparison to other amphisbaenians, which is possibly due to its large body size.

[2] There is no sexual dimorphism in regard to snout-vent length, meristic, or morphometric characters for A. alba most likely due to functional constraints related to their burrowing nature.

[10] When Amphisbaena alba assumes a defensive posture it bends its body into the shape of a horseshoe and raises both the head and the tail.